Cross-Linked Protein Nanostructures Fabricated by Two-Photons Laser Induced Photochemistry
M. IOSIN, S. AŞTILEAN, O. STEPHAN, P.L. BALDECK

Abstract. We report on the laser fabrication of BSA and Fibronectin (Fn) micro-structures using Eosin Y or Rose Bengal photo sensitizers. Similar cross-linking results have been obtained by two-photon absorption using a near-infrared mode-locked Ti:sapphire laser. The microstructure resolution depends on the laser power, but is typi-cally limited by the size of the laser beam within the sample. The biocompatibility of microstructures was demonstrated by observing the specific adhesion of cells on BSA/Fn mixture lines.