of Microspheres and Biocompatible Polymeric Films for Biomimetic Systems
of Molecular Recognition
G. PĂUN, E. NEAGU, V. MOROEANU, B.A. STERIAN, G.L. RADU
Abstract. This study is meant for the obtaining and the
characterization of the biocompatible polymer supports represented by thin
films and chitosan and sodium alginate microspheres. From the structural
point of view these supports are studied by scanning electron microscope (SEM)
and the films’ porosity was determined by Coulter Porometer. After being
activated with carbodiimide and direct immersion, the supports were used
to immobilize urease by different methods, in order to create biomimetic
systems of molecular recognition.
The stability of the obtained enzymatic systems and also the physical
parameters such as: temperature, pH and incubation time influence on those
systems has been studied.
Keywords: biocompatible polymer supports, microspheres, films, chitosan,