Study of Microspheres and Biocompatible Polymeric Films for Biomimetic Systems of Molecular Recognition
G. PĂUN, E. NEAGU, V. MOROEANU, B.A. STERIAN, G.L. RADU

Abstract. This study is meant for the obtaining and the characterization of the biocompatible polymer supports represented by thin films and chitosan and sodium alginate microspheres. From the structural point of view these supports are studied by scanning electron microscope (SEM) and the films’ porosity was determined by Coulter Porometer. After being activated with carbodiimide and direct immersion, the supports were used to immobilize urease by different methods, in order to create biomimetic systems of molecular recognition.
The stability of the obtained enzymatic systems and also the physical parameters such as: temperature, pH and incubation time influence on those systems has been studied.
Keywords: biocompatible polymer supports, microspheres, films, chitosan, alginate, urease.