Clinical and Radiographical Evaluation of Medical Nanotechnologies Based on Stem Cells in Osseous Defects Treatment
R. DASCĂLU, M. SABĂU, V. VÂNĂTU, A. SALA, L. SCHUSZLER, G. TANASIE, V. PĂUNESCU, C. IGNA

Abstract. We proposed in vivo checking of the possibility to use collagenic scaffolds loaded with osteoblasts for tibial bone defects repair on dogs. Evaluation of the healing process was made by serial X-ray – in the postoperatory period, at 30, 45 and 130 days and daily clinical exam. Radiographyc opacity of the drilled foramen and dynamics of the functional troubles were assessed.The X-ray aspect of drilling foramen is new bone tissue like and is correlated with the disappearing of functional troubles at clinical exam.